|
gptkbp:instanceOf
|
gptkb:endogenous_opioid_peptide
peptide
|
|
gptkbp:actsOn
|
gptkb:kappa-opioid_receptor
|
|
gptkbp:aminoAcidSequence
|
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys
|
|
gptkbp:associatedWith
|
gptkb:depression
addiction
chronic pain
stress response
|
|
gptkbp:category
|
neurotransmitter
neuromodulator
opioid peptide
|
|
gptkbp:chemicalFormula
|
C66H111N21O19
|
|
gptkbp:discoveredBy
|
gptkb:Avram_Goldstein
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:effect
|
analgesia
dysphoria
diuresis
inhibition of dopamine release
|
|
gptkbp:encodedBy
|
PDYN gene
|
|
gptkbp:foundIn
|
central nervous system
|
|
gptkbp:function
|
modulation of pain
regulation of stress response
control of emotional state
|
|
gptkbp:hasIsoform
|
dynorphin A
dynorphin B
big dynorphin
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dynorphin
|
|
gptkbp:MeSH_ID
|
D004417
|
|
gptkbp:predecessor
|
gptkb:prodynorphin
|
|
gptkbp:PubChem_CID
|
CHEBI:80264
|
|
gptkbp:relatedTo
|
gptkb:endorphin
gptkb:enkephalin
nociceptin
|
|
gptkbp:UNII
|
6Z5B6HVF6O
|
|
gptkbp:bfsParent
|
gptkb:kappa-opioid_receptor
|
|
gptkbp:bfsLayer
|
7
|