Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
opioid |
| gptkbp:CASNumber |
100587-51-7
|
| gptkbp:criteria |
gptkb:kappa-opioid_receptor
|
| gptkbp:discoveredBy |
Portoghese et al.
|
| gptkbp:discoveredIn |
1987
|
| gptkbp:drugClass |
opioid
|
| gptkbp:effect |
antagonist at kappa-opioid receptor
long-acting kappa-opioid receptor blockade minimal activity at mu- and delta-opioid receptors |
| gptkbp:hasMolecularFormula |
C26H29NO3
|
| https://www.w3.org/2000/01/rdf-schema#label |
nor-BNI
|
| gptkbp:IUPACName |
(2R)-2-[(3R,4R,4aR,7S,7aR,12bS)-3-(cyclopropylmethyl)-4,4a,7,7a-tetrahydro-9-hydroxy-3,4,4a,5,6,7-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3,3-dimethylbutan-2-ol
|
| gptkbp:legalStatus |
not approved for medical use
|
| gptkbp:molecularWeight |
403.51 g/mol
|
| gptkbp:PubChem_CID |
5486971
CHEMBL375295 |
| gptkbp:routeOfAdministration |
subcutaneous
intravenous intraperitoneal |
| gptkbp:structureType |
biphenyl morphinan derivative
|
| gptkbp:studiedBy |
yes
|
| gptkbp:synonym |
nor-binaltorphimine
nor-binaltorphimine dihydrochloride |
| gptkbp:target |
gptkb:kappa-opioid_receptor
|
| gptkbp:UNII |
6J8J1Y1K0O
|
| gptkbp:usedFor |
neuroscience research
study of opioid receptor function |
| gptkbp:bfsParent |
gptkb:kappa-opioid_receptor
|
| gptkbp:bfsLayer |
7
|