Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:KOR
KOR-1 KOR1 kappa opioid receptor opioid receptor, kappa 1 |
| gptkbp:associatedWith |
addiction
mood regulation pain perception |
| gptkbp:discoveredBy |
1993
|
| gptkbp:encodes |
kappa-type opioid receptor
|
| gptkbp:Entrez_Gene_ID |
4985
ENSG00000111249 |
| gptkbp:expressedIn |
central nervous system
peripheral nervous system |
| gptkbp:fullName |
opioid receptor kappa 1
|
| gptkbp:function |
encodes a G-protein coupled receptor
mediates effects of endogenous opioids |
| gptkbp:geneType |
protein-coding
|
| gptkbp:hasTranscriptVariant |
multiple
|
| gptkbp:HGNC_ID |
HGNC:8151
|
| https://www.w3.org/2000/01/rdf-schema#label |
OPRK1 gene
|
| gptkbp:locatedOnChromosome |
chromosome 8
8q11.23 |
| gptkbp:mutationAssociatedWith |
gptkb:depression
schizophrenia alcohol dependence substance dependence |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Oprk1
|
| gptkbp:pathway |
G protein-coupled receptor signaling pathway
opioid signaling pathway |
| gptkbp:product |
kappa-type opioid receptor
|
| gptkbp:target |
kappa opioid receptor agonists
kappa opioid receptor antagonists opioid drugs |
| gptkbp:UniProtID |
gptkb:P41145
|
| gptkbp:bfsParent |
gptkb:opioid
|
| gptkbp:bfsLayer |
6
|