cyclin-dependent kinase 6

URI: https://gptkb.org/entity/cyclin-dependent_kinase_6
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:CDK6
cyclin-dependent kinase 6 isoform 1
gptkbp:associatedWith gptkb:cancer
leukemia
gptkbp:biologicalProcess protein kinase activity
G1/S transition of mitotic cell cycle
gptkbp:cellularComponent gptkb:nucleus
gptkb:cytoplasm
gptkbp:Entrez_Gene_ID gptkb:ENSG00000105810
gptkbp:enzymeClassification serine/threonine protein kinase
gptkbp:function regulation of cell cycle
gptkbp:gene gptkb:CDK6
gptkbp:HGNC_ID HGNC:1777
https://www.w3.org/2000/01/rdf-schema#label cyclin-dependent kinase 6
gptkbp:inhibitedBy gptkb:p16INK4a
gptkb:palbociclib
gptkb:ribociclib
gptkb:abemaciclib
gptkbp:interactsWith gptkb:cyclin_D1
gptkb:cyclin_D2
gptkb:cyclin_D3
gptkbp:length 326
gptkbp:locatedOnChromosome gptkb:7q21.2
gptkbp:molecularWeight 36.5 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB gptkb:1G3N
gptkbp:RefSeq NP_001259.2
gptkbp:UniProtID gptkb:Q00534
gptkbp:bfsParent gptkb:lerociclib
gptkb:Cdk6
gptkb:Cyclin-dependent_kinase_6
gptkb:v-cyclin
gptkbp:bfsLayer 8