|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:c-Ha-ras
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:associatedWith
|
gptkb:oral_squamous_cell_carcinoma
gptkb:cancer
gptkb:Costello_syndrome
bladder cancer
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
signal transduction
GTP binding
GTPase activity
|
|
gptkbp:discoveredBy
|
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
|
|
gptkbp:encodes
|
gptkb:GTPase_HRas
|
|
gptkbp:Entrez_Gene_ID
|
3265
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human HRAS gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11p15.5
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:orthologIn
|
gptkb:mouse_Hras1_gene
gptkb:rat_Hras1_gene
|
|
gptkbp:pathway
|
gptkb:MAPK/ERK_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:proteinFamily
|
gptkb:Ras_family
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:C._elegans_let-60
|
|
gptkbp:bfsLayer
|
5
|