beta-adrenergic receptors

URI: https://gptkb.org/entity/beta-adrenergic_receptors

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:G_protein-coupled_receptor
gptkbp:activatedBy	gptkb:adenylate_cyclase
gptkbp:binds	norepinephrine epinephrine
gptkbp:discoveredBy	gptkb:Raymond_Ahlquist
gptkbp:discoveredIn	1948
gptkbp:encodedBy	gptkb:ADRB1_gene gptkb:ADRB2_gene gptkb:ADRB3_gene
gptkbp:enemyOf	gptkb:salbutamol gptkb:atenolol gptkb:metoprolol gptkb:carvedilol gptkb:dobutamine gptkb:isoproterenol gptkb:labetalol propranolol terbutaline
gptkbp:expressedIn	heart lungs adipose tissue smooth muscle
gptkbp:foundIn	gptkb:cell_membrane
gptkbp:function	mediate sympathetic nervous system responses
https://www.w3.org/2000/01/rdf-schema#label	beta-adrenergic receptors
gptkbp:improves	cyclic AMP
gptkbp:medicalUse	treatment of heart failure treatment of hypertension treatment of asthma treatment of arrhythmia
gptkbp:modulatedBy	phosphorylation desensitization internalization
gptkbp:relatedTo	gptkb:alpha-adrenergic_receptor adrenergic receptor
gptkbp:role	lipolysis vasodilation bronchodilation regulation of heart rate
gptkbp:species	gptkb:human gptkb:mouse right
gptkbp:structure	seven transmembrane domains
gptkbp:subspecies	gptkb:beta-2_adrenergic_receptor gptkb:beta-3_adrenergic_receptor beta-1 adrenergic receptor
gptkbp:target	beta blocker agonist
gptkbp:type	gptkb:Gs_protein
gptkbp:bfsParent	gptkb:Adrenaline
gptkbp:bfsLayer	6