beta-2 adrenergic receptor

URI: https://gptkb.org/entity/beta-2_adrenergic_receptor
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:activatedBy gptkb:adenylate_cyclase
gptkbp:binds norepinephrine
epinephrine
gptkbp:biologicalProcess signal transduction
regulation of heart rate
adrenergic receptor activity
regulation of airway resistance
regulation of vascular tone
gptkbp:discoveredIn 1970s
gptkbp:encodedBy gptkb:ADRB2_gene
gptkbp:Entrez_Gene_ID gptkb:ADRB2
gptkbp:expressedIn gptkb:cancer
gptkb:skeletal_muscle
heart
liver
pancreas
uterus
vascular smooth muscle
gptkbp:foundIn gptkb:human
mammals
gptkbp:hasPolymorphism gptkb:Arg16Gly
gptkb:Gln27Glu
https://www.w3.org/2000/01/rdf-schema#label beta-2 adrenergic receptor
gptkbp:improves gptkb:cAMP
gptkbp:involvedIn vasodilation
smooth muscle relaxation
bronchodilation
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:modulatedBy phosphorylation
desensitization
internalization
gptkbp:PDB gptkb:2RH1
gptkbp:regulates lipolysis
insulin secretion
glycogenolysis
gptkbp:significance gptkb:COPD
asthma
preterm labor
gptkbp:structure seven transmembrane domains
gptkbp:target gptkb:formoterol
gptkb:salmeterol
gptkb:albuterol
gptkb:isoproterenol
beta blockers
terbutaline
beta-2 agonists
gptkbp:UniProtID gptkb:P07550
gptkbp:bfsParent gptkb:beta-adrenergic_receptor
gptkbp:bfsLayer 6