dobutamine

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:drug
synthetic catecholamine
gptkbp:approvedBy 1978
gptkbp:ATCCode C01CA07
gptkbp:CASNumber 343-15-7
gptkbp:chemicalFormula C18H23NO3
gptkbp:contraindication idiopathic hypertrophic subaortic stenosis
gptkbp:discoveredBy gptkb:Eli_Lilly_and_Company
gptkbp:eliminationHalfLife 2 minutes
https://www.w3.org/2000/01/rdf-schema#label dobutamine
gptkbp:KEGGID D07862
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction increases cardiac contractility
beta-1 adrenergic agonist
gptkbp:meltingPoint 198-199°C
gptkbp:metabolism liver
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID CHEMBL1531
36811
DB00841
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect gptkb:arrhythmia
hypertension
angina
tachycardia
gptkbp:solubility water soluble
gptkbp:UNII KJZ4T0802F
gptkbp:usedFor heart failure
cardiogenic shock
cardiac stress testing
gptkbp:bfsParent gptkb:Beta-1_adrenergic_receptor
gptkb:beta-adrenergic_receptors
gptkbp:bfsLayer 7