|
gptkbp:instanceOf
|
hormone
neurotransmitter
|
|
gptkbp:administeredBy
|
injection
inhalation
|
|
gptkbp:agonistOf
|
gptkb:alpha-adrenergic_receptors
gptkb:beta-adrenergic_receptors
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
gptkb:C01CA24
|
|
gptkbp:biosynthesized_from
|
gptkb:tyrosine
|
|
gptkbp:CASNumber
|
51-43-4
|
|
gptkbp:category
|
gptkb:phenylethanolamine
catecholamine
|
|
gptkbp:chemicalFormula
|
C9H13NO3
|
|
gptkbp:color
|
white (as solid)
|
|
gptkbp:contraindication
|
hypertension
narrow-angle glaucoma
cardiac arrhythmias
|
|
gptkbp:discoveredBy
|
gptkb:Jokichi_Takamine
|
|
gptkbp:discoveredIn
|
1901
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:firstSynthesized
|
1904
|
|
gptkbp:foundIn
|
humans
many animals
|
|
gptkbp:function
|
expands air passages of the lungs
increases blood pressure
increases heart rate
participates in fight-or-flight response
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Adrenaline
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:IUPACName
|
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
|
|
gptkbp:legalStatus
|
prescription only (in most countries)
|
|
gptkbp:meltingPoint
|
211–212 °C
|
|
gptkbp:MeSH_ID
|
gptkb:D004481
|
|
gptkbp:metabolism
|
gptkb:catechol-O-methyl_transferase
gptkb:monoamine_oxidase
|
|
gptkbp:molecularWeight
|
183.204 g/mol
|
|
gptkbp:otherName
|
epinephrine
|
|
gptkbp:pKa
|
8.6
|
|
gptkbp:predecessor
|
norepinephrine
|
|
gptkbp:producedBy
|
adrenal glands
medulla of adrenal gland
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL39
5816
|
|
gptkbp:recipient
|
adrenergic receptors
|
|
gptkbp:sideEffect
|
anxiety
headache
hypertension
tremor
palpitations
|
|
gptkbp:solubility
|
soluble
|
|
gptkbp:UNII
|
YZS2R48LPK
|
|
gptkbp:usedAs
|
gptkb:drug
|
|
gptkbp:usedFor
|
cardiac arrest
anaphylaxis
asthma attacks
|
|
gptkbp:bfsParent
|
gptkb:Deftones
|
|
gptkbp:bfsLayer
|
5
|