Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
G protein alpha subunit (Gs)
|
| gptkbp:alternativeName |
adenylyl cyclase
|
| gptkbp:catalyzes |
conversion of ATP to cyclic AMP (cAMP) and pyrophosphate
|
| gptkbp:cofactor |
Mg2+
Mn2+ |
| gptkbp:discoveredBy |
gptkb:Earl_Sutherland
|
| gptkbp:EC_number |
4.6.1.1
|
| gptkbp:foundIn |
gptkb:Bacteria
eukaryotes |
| gptkbp:gene |
gptkb:ADCY1
gptkb:ADCY10 gptkb:ADCY2 gptkb:ADCY3 gptkb:ADCY4 gptkb:ADCY5 gptkb:ADCY6 gptkb:ADCY7 gptkb:ADCY8 gptkb:ADCY9 gptkb:ADCYAP1 |
| https://www.w3.org/2000/01/rdf-schema#label |
adenylate cyclase
|
| gptkbp:inhibitedBy |
G protein alpha subunit (Gi)
|
| gptkbp:involves |
gptkb:cAMP_signaling_pathway
|
| gptkbp:locatedIn |
gptkb:plasma_membrane
|
| gptkbp:product |
cyclic AMP
|
| gptkbp:regulates |
gptkb:forskolin
phosphorylation calcium ions |
| gptkbp:significance |
target for drugs affecting cAMP levels
|
| gptkbp:substrate |
gptkb:ATP
|
| gptkbp:bfsParent |
gptkb:G_protein-coupled_receptor
|
| gptkbp:bfsLayer |
5
|