Statements (64)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:blockade
|
gptkbp:approves |
gptkb:1978
|
gptkbp:atccode |
C07 AB12
|
gptkbp:available_on |
generic drug
|
gptkbp:brand |
gptkb:Tenormin
|
gptkbp:casnumber |
29122-68-7
|
gptkbp:category |
gptkb:D
|
gptkbp:chemical_formula |
C14 H22 N2 O3
|
gptkbp:class |
selective beta-1 adrenergic antagonist
|
gptkbp:clinical_trial |
Phase IV
|
gptkbp:contraindication |
cardiogenic shock
heart block severe bradycardia |
gptkbp:discovered_by |
gptkb:Smith_Kline_Beecham
|
gptkbp:dosage_form |
25-100 mg daily
|
gptkbp:duration |
24 hours
|
gptkbp:excretion |
kidneys
|
gptkbp:formulation |
gptkb:tablet
injection |
https://www.w3.org/2000/01/rdf-schema#label |
atenolol
|
gptkbp:indication |
anxiety
post-myocardial infarction migraine prophylaxis |
gptkbp:interacts_with |
gptkb:diabetes
NSAIDs calcium channel blockers |
gptkbp:is_monitored_by |
blood pressure
heart rate |
gptkbp:lifespan |
6-7 hours
|
gptkbp:metabolism |
liver
|
gptkbp:premiered_on |
1 hour
|
gptkbp:related_products |
gptkb:metoprolol
gptkb:bisoprolol propranolol |
gptkbp:route_of_administration |
oral
intravenous |
gptkbp:side_effect |
gptkb:depression
dizziness fatigue nausea sleep disturbances diarrhea rash joint pain dry mouth shortness of breath weight gain skin rash nightmares hypotension hyperlipidemia muscle cramps hyperglycemia visual disturbances bradycardia thinning hair cold extremities impotence feeling cold |
gptkbp:used_for |
hypertension
arrhythmias angina pectoris |
gptkbp:bfsParent |
gptkb:James_W._Black
|
gptkbp:bfsLayer |
6
|