anaplastic lymphoma kinase (ALK)
GPTKB entity
Statements (69)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:associated_with |
gptkb:healthcare_organization
|
| gptkbp:challenges |
oncogenic activity
|
| gptkbp:clinical_trial |
gptkb:Database_Management_System
therapeutic target |
| gptkbp:code |
gptkb:protein
|
| gptkbp:discovered_by |
gptkb:1994
|
| gptkbp:field_of_study |
molecular biology
oncology |
| gptkbp:genetic_diversity |
gptkb:mythological_figure
|
| https://www.w3.org/2000/01/rdf-schema#label |
anaplastic lymphoma kinase (ALK)
|
| gptkbp:intelligence |
gptkb:video_game
zebrafish rat |
| gptkbp:is_a_route_for |
MAPK signaling pathway
Ras signaling pathway apoptosis regulation cell cycle regulation cell differentiation cell proliferation immune response signal transduction cellular response to stress cell survival synaptic plasticity tumor microenvironment neurogenesis angiogenesis cell adhesion cell migration metastasis stem cell maintenance neurite outgrowth cellular response to growth factor stimulus neural crest development cellular response to DNA damage axon guidance cellular response to bacterial infection cellular response to cytokines cellular response to fungal infection cellular response to hormones cellular response to hypoxia cellular response to ionizing radiation cellular response to mechanical stress cellular response to nutrient levels cellular response to oxidative stress cellular response to parasitic infection cellular response to temperature changes cellular response to viral infection myelination neurotrophic signaling cellular response to p H changes cellular response to stressors P I3 K-Akt signaling pathway differentiation of hematopoietic cells |
| gptkbp:is_aimed_at |
gptkb:alectinib
gptkb:ceritinib gptkb:crizotinib |
| gptkbp:is_involved_in |
cell signaling
tumorigenesis |
| gptkbp:is_represented_in |
gptkb:healthcare_organization
gptkb:neuroblastoma |
| gptkbp:located_in |
chromosome 2
|
| gptkbp:promoter |
gptkb:ALK
|
| gptkbp:type_of |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:bfsParent |
gptkb:Brigatinib
gptkb:Ceritinib gptkb:ceritinib |
| gptkbp:bfsLayer |
6
|