Statements (16)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:associatedWith |
gptkb:anaplastic_large_cell_lymphoma
|
gptkbp:cause |
constitutive activation of ALK tyrosine kinase
|
gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR immunohistochemistry |
gptkbp:discoveredIn |
1994
|
gptkbp:encodes |
NPM-ALK fusion protein
|
gptkbp:hasComponent |
gptkb:ALK_gene
gptkb:NPM1_gene |
https://www.w3.org/2000/01/rdf-schema#label |
NPM-ALK fusion
|
gptkbp:OMIM |
105590
|
gptkbp:result |
gptkb:chromosomal_translocation_t(2;5)(p23;q35)
|
gptkbp:target |
ALK inhibitors
|
gptkbp:bfsParent |
gptkb:anaplastic_lymphoma_kinase_(ALK)
|
gptkbp:bfsLayer |
7
|