Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:binds |
norepinephrine
epinephrine |
| gptkbp:discoveredBy |
gptkb:Raymond_Ahlquist
|
| gptkbp:discoveredIn |
1948
|
| gptkbp:encodedBy |
gptkb:ADRA1A_gene
gptkb:ADRA1B_gene gptkb:ADRA1D_gene gptkb:ADRA2A_gene gptkb:ADRA2B_gene gptkb:ADRA2C_gene |
| gptkbp:enemyOf |
gptkb:phentolamine
gptkb:prazosin gptkb:phenylephrine gptkb:clonidine |
| gptkbp:foundIn |
central nervous system
blood vessels smooth muscle |
| gptkbp:function |
vasoconstriction
increase blood pressure increase peripheral resistance |
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-adrenergic receptors
|
| gptkbp:involvedIn |
fight-or-flight response
sympathetic nervous system |
| gptkbp:modulatedBy |
neurotransmitter release
smooth muscle contraction |
| gptkbp:subclassOf |
adrenergic receptor
|
| gptkbp:subspecies |
gptkb:alpha-1_adrenergic_receptor
gptkb:alpha-2_adrenergic_receptor |
| gptkbp:bfsParent |
gptkb:Adrenaline
|
| gptkbp:bfsLayer |
6
|