Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:G_protein-coupled_receptor
adrenergic receptor |
| gptkbp:activatedBy |
Gq/11 protein
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
gptkb:ADRA1A_gene
gptkb:ADRA1B_gene gptkb:ADRA1D_gene |
| gptkbp:enemyOf |
gptkb:prazosin
gptkb:phenylephrine doxazosin methoxamine |
| gptkbp:foundIn |
gptkb:prostate
heart central nervous system liver vascular smooth muscle |
| gptkbp:function |
smooth muscle contraction
vasoconstriction increase in blood pressure |
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-1 adrenergic receptor
|
| gptkbp:improves |
intracellular calcium
|
| gptkbp:ligand |
norepinephrine
epinephrine |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:subspecies |
adrenergic receptor
alpha-1A adrenergic receptor alpha-1B adrenergic receptor alpha-1D adrenergic receptor |
| gptkbp:target |
decongestants
antihypertensive drugs |
| gptkbp:type |
phospholipase C activation
|
| gptkbp:bfsParent |
gptkb:alpha-adrenergic_receptors
|
| gptkbp:bfsLayer |
7
|