Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
vasoconstriction
neurotransmitter release inhibition noradrenergic signaling |
| gptkbp:encodes |
Alpha-2B adrenergic receptor
|
| gptkbp:Entrez_Gene_ID |
151
ENSG00000150594 |
| gptkbp:expressedIn |
brain
vascular smooth muscle |
| gptkbp:function |
regulates neurotransmitter release
regulates vascular tone mediates inhibition of adenylate cyclase |
| gptkbp:hasPolymorphism |
deletion variant (301-303del) in coding region
|
| gptkbp:HGNC_ID |
gptkb:HGNC:286
|
| https://www.w3.org/2000/01/rdf-schema#label |
ADRA2B gene
|
| gptkbp:locatedOnChromosome |
chromosome 2
2p13-q13 |
| gptkbp:OMIM |
104260
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:polymorphismAssociatedWith |
emotional memory
risk of cardiovascular disease |
| gptkbp:product |
ADRA2B protein
|
| gptkbp:receptorSubtype |
gptkb:alpha-2_adrenergic_receptor
|
| gptkbp:recipient |
gptkb:G_protein-coupled_receptor
|
| gptkbp:UniProtID |
P18089
|
| gptkbp:bfsParent |
gptkb:alpha-adrenergic_receptors
|
| gptkbp:bfsLayer |
7
|