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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alias
|
ADRA1B
alpha-1B-adrenergic receptor
alpha1BAR
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|
gptkbp:associatedWith
|
gptkb:neuroblastoma
gptkb:pheochromocytoma
cell proliferation
prostate cancer
vasoconstriction
blood pressure regulation
|
|
gptkbp:biologicalProcess
|
signal transduction
regulation of blood pressure
adrenergic receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gene cloning
|
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gptkbp:encodes
|
Alpha-1B adrenergic receptor
|
|
gptkbp:Entrez_Gene_ID
|
147
ENSG00000170214
GC05P146285
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
heart
liver
|
|
gptkbp:firstDescribed
|
1989
|
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gptkbp:function
|
encodes a G protein-coupled receptor
mediates physiological effects of catecholamines
|
|
gptkbp:GOID
|
GO:0007186
GO:0004936
|
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gptkbp:hasTranscriptVariant
|
multiple splice variants
|
|
gptkbp:HGNC_ID
|
HGNC:282
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ADRA1B gene
|
|
gptkbp:length
|
519 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5q33.3
|
|
gptkbp:MIM_number
|
104220
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
hypertension
|
|
gptkbp:OMIM
|
104220
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Adra1b
|
|
gptkbp:pathway
|
G protein-coupled receptor signaling pathway
adrenergic signaling pathway
|
|
gptkbp:product
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:proteinFamily
|
gptkb:adrenergic_receptor_family
|
|
gptkbp:RefSeq
|
NM_000679
|
|
gptkbp:UniProtID
|
P35368
|
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gptkbp:bfsParent
|
gptkb:alpha-adrenergic_receptors
|
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gptkbp:bfsLayer
|
7
|