|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:drug
|
|
gptkbp:ATCCode
|
C04AB01
|
|
gptkbp:brand
|
Regitine
|
|
gptkbp:CASNumber
|
50-60-2
|
|
gptkbp:chemicalFormula
|
C17H19N3O
|
|
gptkbp:contraindication
|
myocardial infarction
coronary artery disease
|
|
gptkbp:discoveredBy
|
gptkb:Novartis
|
|
gptkbp:hasInChIKey
|
gptkb:QFFGVLORLPOAEC-UHFFFAOYSA-N
|
|
gptkbp:hasSMILES
|
C1CN=C(N1)CC(C2=CC=CC=C2)C(=O)N
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
phentolamine
|
|
gptkbp:IUPACName
|
3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-1-phenyl-2-propan-1-one
|
|
gptkbp:KEGGID
|
D08385
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
non-selective alpha-adrenergic antagonist
|
|
gptkbp:meltingPoint
|
168-173 °C
|
|
gptkbp:molecularWeight
|
281.36 g/mol
|
|
gptkbp:PubChem_CID
|
4908
CHEMBL1201
DB00692
|
|
gptkbp:routeOfAdministration
|
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
gptkb:arrhythmia
nasal congestion
hypotension
tachycardia
gastrointestinal upset
|
|
gptkbp:UNII
|
5PG9HQW8QH
|
|
gptkbp:usedFor
|
treatment of hypertensive emergencies
diagnosis of pheochromocytoma
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
false
|
|
gptkbp:bfsParent
|
gptkb:alpha-adrenergic_receptors
|
|
gptkbp:bfsLayer
|
7
|