|
gptkbp:instanceOf
|
gptkb:drug
alpha-1 adrenergic receptor antagonist
|
|
gptkbp:approvalYear
|
1976
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
C02CA01
|
|
gptkbp:brand
|
Minipress
|
|
gptkbp:CASNumber
|
19216-56-9
|
|
gptkbp:chemicalFormula
|
C19H21N5O4
|
|
gptkbp:contraindication
|
hypersensitivity to prazosin
|
|
gptkbp:discoveredBy
|
gptkb:Pfizer
|
|
gptkbp:drugClass
|
antihypertensive
sympatholytic
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
prazosin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
blocks alpha-1 adrenergic receptors
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gptkb:orthostatic_hypotension
nausea
dizziness
headache
drowsiness
palpitations
|
|
gptkbp:synonym
|
Minipress
Prazosin hydrochloride
|
|
gptkbp:usedFor
|
gptkb:post-traumatic_stress_disorder
gptkb:Raynaud's_phenomenon
gptkb:benign_prostatic_hyperplasia
hypertension
|
|
gptkbp:bfsParent
|
gptkb:alpha-adrenergic_receptors
|
|
gptkbp:bfsLayer
|
7
|