|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:affects
|
central nervous system
blood pressure
|
|
gptkbp:approvedBy
|
1974
|
|
gptkbp:ATCCode
|
C02AC01
|
|
gptkbp:availableOn
|
gptkb:tablet
musical composition
injection
|
|
gptkbp:brand
|
Catapres
Kapvay
|
|
gptkbp:CASNumber
|
4205-90-7
|
|
gptkbp:chemicalFormula
|
imidazoline derivative
|
|
gptkbp:contraindication
|
hypersensitivity to clonidine
|
|
gptkbp:discoveredBy
|
gptkb:Boehringer_Ingelheim
|
|
gptkbp:drugClass
|
alpha-2 adrenergic agonist
|
|
gptkbp:eliminationHalfLife
|
6–24 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C9H9Cl2N3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
clonidine
|
|
gptkbp:interactsWith
|
gptkb:tricyclic_antidepressants
gptkb:CNS_depressants
beta blockers
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
stimulates alpha-2 adrenergic receptors
|
|
gptkbp:MedlinePlusID
|
a682243
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseSymptoms
|
hypotension
respiratory depression
bradycardia
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
2803
DB00575
|
|
gptkbp:routeOfAdministration
|
oral
transdermal
epidural
|
|
gptkbp:sideEffect
|
constipation
dizziness
fatigue
drowsiness
hypotension
dry mouth
bradycardia
|
|
gptkbp:UNII
|
MN3L5RMN02
|
|
gptkbp:usedFor
|
ADHD
sleep disorders
hypertension
Tourette syndrome
anxiety disorders
opioid withdrawal
menopausal hot flashes
|
|
gptkbp:bfsParent
|
gptkb:alpha-adrenergic_receptors
gptkb:Atenolol
|
|
gptkbp:bfsLayer
|
7
|