Tumor necrosis factor receptor superfamily member 1B

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:CD120b gptkb:TNFR2
gptkbp:associatedWith	gptkb:cancer autoimmune diseases inflammatory diseases
gptkbp:binds	gptkb:tumor_necrosis_factor_alpha
gptkbp:discoveredIn	1990s
gptkbp:domain	extracellular domain transmembrane domain cytoplasmic domain
gptkbp:encodedBy	gptkb:TNFRSF1B_gene
gptkbp:Entrez_Gene_ID	7133
gptkbp:expressedIn	gptkb:neurons endothelial cells immune cells
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	involved in inflammation regulates apoptosis mediates immune response
gptkbp:HGNC_ID	11917
gptkbp:interactsWith	gptkb:TRADD gptkb:TRAF2 gptkb:TRAF1
gptkbp:ligand	gptkb:TNF-alpha gptkb:lymphotoxin-alpha
gptkbp:locatedIn	gptkb:cell_membrane
gptkbp:locatedOnChromosome	gptkb:1p36.22
gptkbp:memberOf	gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:molecularWeight	48 kDa
gptkbp:OMIM	191191
gptkbp:structure	type I membrane protein
gptkbp:type	gptkb:MAPK_pathway gptkb:JNK_pathway gptkb:NF-kappaB_pathway
gptkbp:UniProtID	gptkb:P20333
gptkbp:bfsParent	gptkb:CD120b gptkb:TNFR2
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	Tumor necrosis factor receptor superfamily member 1B