Tumor necrosis factor receptor superfamily member 1B

URI: https://gptkb.org/entity/Tumor_necrosis_factor_receptor_superfamily_member_1B
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CD120b
gptkb:TNFR2
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
inflammatory diseases
gptkbp:binds gptkb:tumor_necrosis_factor_alpha
gptkbp:discoveredIn 1990s
gptkbp:domain extracellular domain
transmembrane domain
cytoplasmic domain
gptkbp:encodedBy gptkb:TNFRSF1B_gene
gptkbp:Entrez_Gene_ID 7133
gptkbp:expressedIn neurons
endothelial cells
immune cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function involved in inflammation
regulates apoptosis
mediates immune response
gptkbp:HGNC_ID 11917
https://www.w3.org/2000/01/rdf-schema#label Tumor necrosis factor receptor superfamily member 1B
gptkbp:interactsWith gptkb:TRADD
gptkb:TRAF2
gptkb:TRAF1
gptkbp:ligand gptkb:TNF-alpha
gptkb:lymphotoxin-alpha
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome gptkb:1p36.22
gptkbp:memberOf gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:molecularWeight 48 kDa
gptkbp:OMIM 191191
gptkbp:structure type I membrane protein
gptkbp:type gptkb:MAPK_pathway
gptkb:JNK_pathway
gptkb:NF-kappaB_pathway
gptkbp:UniProtID gptkb:P20333
gptkbp:bfsParent gptkb:TNFR2
gptkbp:bfsLayer 7