|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
LT-alpha
tumor necrosis factor-beta
|
|
gptkbp:associatedWith
|
autoimmune diseases
inflammatory diseases
|
|
gptkbp:discoveredIn
|
1960s
|
|
gptkbp:encodedBy
|
gptkb:LTA_gene
|
|
gptkbp:Entrez_Gene_ID
|
4049
|
|
gptkbp:expressedIn
|
immune system
|
|
gptkbp:formsComplexWith
|
lymphotoxin-beta
|
|
gptkbp:function
|
cytokine
mediates inflammation
induces cell death
|
|
gptkbp:gene
|
gptkb:LTA
|
|
gptkbp:HGNC_ID
|
6720
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
lymphotoxin-alpha
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_superfamily
|
|
gptkbp:molecularWeight
|
25 kDa
|
|
gptkbp:OMIM
|
153440
|
|
gptkbp:producedBy
|
activated lymphocytes
|
|
gptkbp:recipient
|
gptkb:TNFRSF1A
gptkb:TNFRSF1B
LTβR
|
|
gptkbp:role
|
apoptosis
lymphoid organ development
regulation of immune response
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
homotrimer
heterotrimer with lymphotoxin-beta
|
|
gptkbp:UniProtID
|
P01374
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor-alpha
gptkb:TNFR1
gptkb:LTA_gene
|
|
gptkbp:bfsLayer
|
7
|