|
gptkbp:instanceOf
|
gptkb:T_helper_cell_subtype
|
|
gptkbp:differentiationInducedBy
|
gptkb:interferon-gamma
gptkb:interleukin-12
|
|
gptkbp:discoveredBy
|
Timothy Mosmann
|
|
gptkbp:enemyOf
|
gptkb:Th2_cells
|
|
gptkbp:expressedIn
|
gptkb:STAT4
gptkb:IFNGR1
T-bet
|
|
gptkbp:function
|
cell-mediated immunity
|
|
gptkbp:inhibitedBy
|
gptkb:interleukin-4
Th2 cytokines
|
|
gptkbp:involvedIn
|
macrophage activation
B cell class switching to IgG2a
delayed-type hypersensitivity
|
|
gptkbp:location
|
lymph nodes
peripheral blood
sites of inflammation
|
|
gptkbp:mainCytokine
|
gptkb:interferon-gamma
|
|
gptkbp:marking
|
gptkb:CXCR3
gptkb:CD4
gptkb:CCR5
|
|
gptkbp:originatedIn
|
naive CD4+ T cells
|
|
gptkbp:regulates
|
T-bet
|
|
gptkbp:role
|
autoimmune diseases
chronic inflammation
intracellular pathogen defense
tuberculosis immunity
|
|
gptkbp:secretes
|
gptkb:interferon-gamma
gptkb:interleukin-2
gptkb:tumor_necrosis_factor_alpha
|
|
gptkbp:subclassOf
|
gptkb:CD4+_T_cells
|
|
gptkbp:bfsParent
|
gptkb:CD4+_T_cells
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Th1 cells
|