CXCR3

GPTKB entity

Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName CD183
GPR9
chemokine (C-X-C motif) receptor 3
gptkbp:associatedWith autoimmune diseases
inflammatory diseases
gptkbp:binds gptkb:CXCL11
gptkb:CXCL10
gptkb:CXCL9
gptkbp:discoveredIn 1996
gptkbp:encodedBy CXCR3 gene
gptkbp:Entrez_Gene_ID 2833
ENSG00000186810
gptkbp:expressedIn gptkb:natural_killer_cells
some epithelial cells
activated T lymphocytes
gptkbp:externalLink https://www.ncbi.nlm.nih.gov/gene/2833
https://www.uniprot.org/uniprot/P49682
gptkbp:fullName C-X-C chemokine receptor type 3
gptkbp:function gptkb:G_protein-coupled_receptor
chemokine receptor
gptkbp:HGNC_ID 2561
https://www.w3.org/2000/01/rdf-schema#label CXCR3
gptkbp:involvedIn immune response
T cell migration
gptkbp:locatedOnChromosome gptkb:X_chromosome
Xq13
gptkbp:modulatedBy inflammation
cell trafficking
gptkbp:OMIM 300574
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:regulates immune cell trafficking
Th1 cell recruitment
gptkbp:structureType seven-transmembrane domain protein
gptkbp:target therapeutic antibodies
small molecule inhibitors
gptkbp:type G protein-coupled signaling
gptkbp:UniProtID P49682
gptkbp:bfsParent gptkb:Th1_cells
gptkbp:bfsLayer 7