|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
CIS2
SSI2
STAT-induced STAT inhibitor 2
|
|
gptkbp:associatedWith
|
immune response
growth hormone signaling
|
|
gptkbp:chromosomeArm
|
12q
|
|
gptkbp:discoveredBy
|
Yoshimura et al.
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
SOCS2 protein
|
|
gptkbp:Entrez_Gene_ID
|
8835
ENSG00000136158
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
heart
liver
spleen
|
|
gptkbp:fullName
|
Suppressor of Cytokine Signaling 2
|
|
gptkbp:function
|
negative regulation of cytokine signaling
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:19392
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SOCS2
|
|
gptkbp:interactsWith
|
gptkb:JAK2
gptkb:STAT5A
gptkb:STAT5B
|
|
gptkbp:length
|
198 amino acids
|
|
gptkbp:locatedOnChromosome
|
12
12q21-q23
|
|
gptkbp:molecularWeight
|
22 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
growth hormone insensitivity
|
|
gptkbp:OMIM
|
604005
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Socs2
|
|
gptkbp:proteinFamily
|
gptkb:SOCS_box
SH2 domain
|
|
gptkbp:regulates
|
gptkb:JAK-STAT_signaling_pathway
gptkb:growth_hormone_receptor
gptkb:interleukin-6_receptor
gptkb:insulin-like_growth_factor_1_receptor
gptkb:prolactin_receptor
erythropoietin receptor
induced by cytokines
induced by growth hormone
induced by prolactin
|
|
gptkbp:UniProtID
|
O14508
|
|
gptkbp:bfsParent
|
gptkb:SOCS
gptkb:SOCS_family
gptkb:miR-194
gptkb:SOCS_proteins
gptkb:Cish_(mouse_gene)
|
|
gptkbp:bfsLayer
|
7
|