Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:cell_surface_receptor |
| gptkbp:alternativeName |
gptkb:CD126
gptkb:IL-6R |
| gptkbp:associatedWith |
gptkb:Castleman_disease
rheumatoid arthritis |
| gptkbp:biologicalProcess |
gptkb:immune_response
inflammatory response cytokine receptor activity |
| gptkbp:component |
gptkb:IL6R_alpha_chain
gp130 (IL6ST) |
| gptkbp:encodedBy |
gptkb:IL6R_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
binds interleukin-6
mediates IL-6 signaling |
| gptkbp:gene |
gptkb:IL6R
|
| gptkbp:HGNC_ID |
6018
|
| gptkbp:locatedOnChromosome |
1q21
|
| gptkbp:location |
gptkb:cell_membrane
soluble form in plasma |
| gptkbp:OMIM |
147880
|
| gptkbp:PDB |
1N26
|
| gptkbp:symbol |
gptkb:IL6R
|
| gptkbp:targetOfDrug |
gptkb:tocilizumab
gptkb:sarilumab |
| gptkbp:UniProtID |
P08887
|
| gptkbp:bfsParent |
gptkb:Kevzara
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
interleukin-6 receptor
|