Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
gptkbp:alternativeName |
gptkb:CD126
gptkb:IL-6R |
gptkbp:associatedWith |
gptkb:Castleman_disease
rheumatoid arthritis |
gptkbp:biologicalProcess |
immune response
inflammatory response cytokine receptor activity |
gptkbp:component |
gptkb:IL6R_alpha_chain
gp130 (IL6ST) |
gptkbp:encodedBy |
gptkb:IL6R_gene
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
binds interleukin-6
mediates IL-6 signaling |
gptkbp:gene |
gptkb:IL6R
|
gptkbp:HGNC_ID |
6018
|
https://www.w3.org/2000/01/rdf-schema#label |
interleukin-6 receptor
|
gptkbp:locatedOnChromosome |
1q21
|
gptkbp:location |
gptkb:cell_membrane
soluble form in plasma |
gptkbp:OMIM |
147880
|
gptkbp:PDB |
1N26
|
gptkbp:symbol |
gptkb:IL6R
|
gptkbp:targetOfDrug |
gptkb:tocilizumab
gptkb:sarilumab |
gptkbp:UniProtID |
P08887
|
gptkbp:bfsParent |
gptkb:Kevzara
|
gptkbp:bfsLayer |
6
|