Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:discoveredIn |
1997
|
| gptkbp:domain |
gptkb:SOCS_box
SH2 domain |
| gptkbp:expressedIn |
immune cells
|
| gptkbp:foundIn |
mammals
|
| gptkbp:function |
negative feedback regulator of cytokine signaling
|
| gptkbp:hasMember |
gptkb:SOCS1
gptkb:SOCS2 gptkb:SOCS3 gptkb:SOCS4 gptkb:SOCS5 gptkb:SOCS6 gptkb:SOCS7 gptkb:CISH |
| https://www.w3.org/2000/01/rdf-schema#label |
SOCS
|
| gptkbp:inhibitedBy |
gptkb:STAT_transcription_factors
gptkb:JAK_kinases |
| gptkbp:involves |
gptkb:cancer
autoimmune diseases inflammatory diseases |
| gptkbp:regulates |
cytokine signaling
|
| gptkbp:relatedTo |
gptkb:JAK-STAT_signaling_pathway
|
| gptkbp:standsFor |
gptkb:Suppressor_of_Cytokine_Signaling
|
| gptkbp:bfsParent |
gptkb:CIS_(gene)
gptkb:CISH |
| gptkbp:bfsLayer |
6
|