|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
MADH1
Mothers against decapentaplegic homolog 1
|
|
gptkbp:associatedWith
|
gptkb:cancer
cell differentiation
embryogenesis
developmental processes
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodedBy
|
SMAD1 gene
|
|
gptkbp:Entrez_Gene_ID
|
4086
ENSG00000170365
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
6767
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SMAD1
|
|
gptkbp:interactsWith
|
gptkb:BMPR1A
gptkb:BMPR1B
gptkb:SMAD5
gptkb:SMAD8
gptkb:SMAD4
|
|
gptkbp:involvedIn
|
gptkb:BMP_signaling_pathway
gptkb:TGF-beta_signaling_pathway
|
|
gptkbp:length
|
465
|
|
gptkbp:locatedOnChromosome
|
chromosome 4q31.21
|
|
gptkbp:memberOf
|
gptkb:SMAD_family
gptkb:SMAD_proteins
|
|
gptkbp:molecularWeight
|
52 kDa
|
|
gptkbp:OMIM
|
601595
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
|
|
gptkbp:PDB
|
3GMJ
|
|
gptkbp:phosphorylates
|
BMP type I receptors
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
gptkb:SMURF1
gptkb:SMURF2
apoptosis
gene expression
angiogenesis
osteoblast differentiation
microRNAs
|
|
gptkbp:structure
|
MH1 domain
MH2 domain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q15797
|
|
gptkbp:bfsParent
|
gptkb:SMAD_family
gptkb:SMAD
gptkb:SMURF1
gptkb:BMPR1A
|
|
gptkbp:bfsLayer
|
7
|