|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD292
ALK3
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:encodes
|
BMPR1A protein
|
|
gptkbp:Entrez_Gene_ID
|
657
ENSG00000107779
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
bone morphogenetic protein receptor type 1A
|
|
gptkbp:function
|
cell surface receptor
serine/threonine kinase receptor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
1076
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BMPR1A
|
|
gptkbp:interactsWith
|
gptkb:BMP2
gptkb:BMP4
gptkb:SMAD_proteins
|
|
gptkbp:involves
|
gptkb:BMP_signaling_pathway
embryonic development
cell growth regulation
osteogenesis
|
|
gptkbp:length
|
532
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:plasma_membrane
10q23.2
|
|
gptkbp:molecularWeight
|
57 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:juvenile_polyposis_syndrome
colorectal cancer
hereditary mixed polyposis syndrome
|
|
gptkbp:OMIM
|
601299
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Bmpr1a
|
|
gptkbp:orthologInZebrafish
|
bmpr1aa
|
|
gptkbp:PDB
|
3MDY
|
|
gptkbp:phosphorylates
|
gptkb:SMAD1
gptkb:SMAD5
gptkb:SMAD8
|
|
gptkbp:proteinFamily
|
gptkb:TGF-beta_receptor_family
|
|
gptkbp:RefSeq
|
NM_004329
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
proliferation
|
|
gptkbp:reviewedBy
|
gptkb:GeneReviews
gptkb:OMIM
gptkb:UniProtKB
|
|
gptkbp:UniProtID
|
P36894
|
|
gptkbp:bfsParent
|
gptkb:10q23.3
|
|
gptkbp:bfsLayer
|
6
|