|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
GTP binding
|
|
gptkbp:alternativeName
|
gptkb:Ras_homolog_enriched_in_brain
gptkb:RHEB1
|
|
gptkbp:associatedWith
|
gptkb:tuberous_sclerosis_complex
|
|
gptkbp:decommissioned
|
GDP binding
|
|
gptkbp:encodes
|
gptkb:Ras_homolog_enriched_in_brain_protein
|
|
gptkbp:Entrez_Gene_ID
|
6009
ENSG00000106615
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
|
|
gptkbp:function
|
GTP binding
GTPase activity
regulation of mTOR signaling pathway
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:RHEBL1
|
|
gptkbp:HGNC_ID
|
HGNC:10018
|
|
gptkbp:inhibitedBy
|
gptkb:TSC2
|
|
gptkbp:interactsWith
|
gptkb:TSC1
gptkb:TSC2
gptkb:FKBP38
|
|
gptkbp:locatedOnChromosome
|
chromosome 7q36.1 (human)
|
|
gptkbp:location
|
gptkb:lysosome
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:memberOf
|
gptkb:Ras_superfamily
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:intellectual_disability
gptkb:cancer
epilepsy
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
gptkb:2Q3L
1XTQ
3OES
|
|
gptkbp:postTranslationalModification
|
farnesylation
phosphorylation
|
|
gptkbp:regulates
|
gptkb:TSC1/TSC2_complex
gptkb:mTORC1
cell proliferation
cell growth
protein synthesis
autophagy
|
|
gptkbp:UniProtID
|
Q15382
|
|
gptkbp:bfsParent
|
gptkb:Ras_gene_family
|
|
gptkbp:bfsLayer
|
5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RHEB
|