Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
cell growth regulation
oncogenesis |
| gptkbp:evolvesFrom |
eukaryotes
|
| gptkbp:foundIn |
gptkb:HRAS
gptkb:KRAS gptkb:NRAS gptkb:Mus_musculus gptkb:ARF_proteins gptkb:RAB_proteins gptkb:RHO_proteins gptkb:Homo_sapiens gptkb:Caenorhabditis_elegans gptkb:Drosophila_melanogaster gptkb:Ras_superfamily_proteins gptkb:RAN_proteins |
| gptkbp:function |
GTP binding
GTP hydrolysis |
| gptkbp:GO_term |
GTPase activity
small GTPase mediated signal transduction |
| https://www.w3.org/2000/01/rdf-schema#label |
Ras family GTPase domain
|
| gptkbp:InterPro |
gptkb:IPR001806
|
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:length |
~170 amino acids
|
| gptkbp:motif |
gptkb:P-loop
gptkb:Switch_II_region gptkb:Switch_I_region |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:proteinFamily |
gptkb:PF00071
|
| gptkbp:SCOP |
c.37.1.8
|
| gptkbp:structure |
alpha/beta fold
|
| gptkbp:bfsParent |
gptkb:PF00057
gptkb:PF00071 |
| gptkbp:bfsLayer |
7
|