P-loop

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf protein structural motif
gptkbp:alsoKnownAs phosphate-binding loop
gptkbp:binds phosphate groups of nucleotides
gptkbp:conservedIn across many species
gptkbp:firstDescribed 1982
Walker et al.
gptkbp:foundIn gptkb:nucleotide-binding_proteins
gptkbp:function stabilizes binding of nucleotide phosphates
https://www.w3.org/2000/01/rdf-schema#label P-loop
gptkbp:InterPro gptkb:IPR027417
gptkbp:locatedIn N-terminal region of proteins
gptkbp:motif GxxxxGK[S/T]
gptkbp:mutationAssociatedWith loss of nucleotide binding
gptkbp:presentIn gptkb:ATPases
gptkb:helicases
gptkb:kinases
GTPases
motor proteins
gptkbp:proteinFamily gptkb:PF00025
gptkbp:SCOPID 2004.1
gptkbp:structure loop between beta strand and alpha helix
gptkbp:bfsParent gptkb:GTP-binding_domain
gptkbp:bfsLayer 6