Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:contains |
conserved amino acid motifs
|
| gptkbp:foundIn |
gptkb:GTPase_proteins
|
| gptkbp:function |
conformational change upon GTP hydrolysis
|
| https://www.w3.org/2000/01/rdf-schema#label |
Switch II region
|
| gptkbp:importantFor |
GTP binding
GTP hydrolysis |
| gptkbp:interactsWith |
effector proteins
regulatory proteins |
| gptkbp:involvedIn |
signal transduction
|
| gptkbp:mutationAssociatedWith |
can lead to constitutive activation
can lead to loss of function |
| gptkbp:structuralChange |
switches between active and inactive states
|
| gptkbp:studiedIn |
gptkb:Ras_protein_family
gptkb:Rab_GTPases gptkb:Rho_GTPases |
| gptkbp:bfsParent |
gptkb:GTP-binding_domain
gptkb:3265_(HRAS) |
| gptkbp:bfsLayer |
6
|