|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:FAK2
gptkb:PYK2
gptkb:RAFTK
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
|
|
gptkbp:biologicalProcess
|
signal transduction
ATP binding
cell adhesion
protein kinase activity
regulation of cell shape
response to calcium ion
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
gptkb:plasma_membrane
focal adhesion
|
|
gptkbp:discoveredBy
|
Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J (1995)
|
|
gptkbp:encodes
|
gptkb:Protein_tyrosine_kinase_2_beta
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000120899
2185
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:cancer
brain
heart
liver
|
|
gptkbp:function
|
non-receptor protein tyrosine kinase
|
|
gptkbp:HGNC_ID
|
9612
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTK2B
|
|
gptkbp:interactsWith
|
gptkb:SRC
gptkb:Paxillin
gptkb:GRB2
gptkb:Dynamin
gptkb:STAT3
|
|
gptkbp:involvedIn
|
cell migration
cell signaling
regulation of cytoskeleton
calcium-induced signaling
|
|
gptkbp:locatedOnChromosome
|
gptkb:8p21.2
chromosome 8
|
|
gptkbp:OMIM
|
600758
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptk2b
|
|
gptkbp:phosphorylates
|
gptkb:paxillin
gptkb:STAT3
|
|
gptkbp:regulates
|
activated by G-protein coupled receptors
activated by increased intracellular calcium
activated by integrin engagement
|
|
gptkbp:UniProtID
|
gptkb:Q14289
|
|
gptkbp:bfsParent
|
gptkb:Alzheimer's_disease_pathway
gptkb:KDR_gene
|
|
gptkbp:bfsLayer
|
7
|