Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
cancer progression
integrin signaling focal adhesion kinase signaling |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
LD motifs
LIM domains |
| gptkbp:encodedBy |
PXN gene
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:foundIn |
focal adhesions
|
| gptkbp:function |
signal transduction
cell adhesion cytoskeletal organization |
| https://www.w3.org/2000/01/rdf-schema#label |
Paxillin
|
| gptkbp:interactsWith |
gptkb:actin
gptkb:FAK gptkb:integrins gptkb:Src_family_kinases gptkb:vinculin |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~68 kDa
|
| gptkbp:phosphorylates |
gptkb:Src
gptkb:FAK |
| gptkbp:role |
cell migration
cell motility cancer metastasis mechanotransduction |
| gptkbp:UniProtID |
P49023
|
| gptkbp:bfsParent |
gptkb:PTK2B
|
| gptkbp:bfsLayer |
8
|