Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
PXN
focal adhesion phosphoprotein p125 |
| gptkbp:discoveredBy |
Keith Burridge
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:domain |
LD motifs
LIM domains |
| gptkbp:encodedBy |
PXN gene
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:foundIn |
focal adhesions
|
| gptkbp:function |
signal transduction
cell adhesion scaffold protein |
| https://www.w3.org/2000/01/rdf-schema#label |
paxillin
|
| gptkbp:interactsWith |
gptkb:FAK
gptkb:integrins gptkb:Src_family_kinases gptkb:vinculin actin cytoskeleton |
| gptkbp:locale |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
chromosome 12q24.23
|
| gptkbp:molecularWeight |
68 kDa
|
| gptkbp:OMIM |
602768
|
| gptkbp:phosphorylates |
gptkb:Src
gptkb:FAK |
| gptkbp:role |
cell migration
cytoskeletal organization cancer metastasis |
| gptkbp:UniProtID |
P49023
|
| gptkbp:bfsParent |
gptkb:PTK2
|
| gptkbp:bfsLayer |
6
|