|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:mechanistic_target_of_rapamycin
gptkb:FK506-binding_protein_12-rapamycin-associated_protein_1
gptkb:FRAP
RAFT1
RAPT1
|
|
gptkbp:associatedWith
|
gptkb:tuberous_sclerosis
gptkb:cancer
epilepsy
neurodevelopmental disorders
|
|
gptkbp:biologicalProcess
|
cell proliferation
cell growth
protein synthesis
kinase activity
autophagy
|
|
gptkbp:catalyzes
|
ATP + a protein = ADP + a phosphoprotein
|
|
gptkbp:enzymeClassification
|
EC 2.7.11.1
|
|
gptkbp:gene
|
gptkb:MTOR
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P49815
|
|
gptkbp:inhibitedBy
|
gptkb:rapamycin
gptkb:torin1
PP242
|
|
gptkbp:interactsWith
|
gptkb:AKT1
gptkb:DEPTOR
gptkb:MLST8
gptkb:TSC1
gptkb:TSC2
gptkb:RPTOR
|
|
gptkbp:length
|
2549
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.2
chr1:111,065,398-111,440,921
|
|
gptkbp:molecularWeight
|
289,509
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Mtor
|
|
gptkbp:pathway
|
gptkb:mTOR_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:5FLC
gptkb:6BCU
4JSV
6BCX
|
|
gptkbp:phosphorylates
|
Ser2448
Ser2481
|
|
gptkbp:protein_name
|
gptkb:Serine/threonine-protein_kinase_mTOR
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subcellularLocation
|
gptkb:lysosome
gptkb:nucleus
gptkb:cytoplasm
endoplasmic reticulum membrane
|
|
gptkbp:UniProtID
|
gptkb:P49815
|
|
gptkbp:bfsParent
|
gptkb:TSC2
|
|
gptkbp:bfsLayer
|
6
|