|
gptkbp:instanceOf
|
gptkb:UniProt_accession_number
|
|
gptkbp:alternativeName
|
gptkb:Antigen_NY-CO-13
gptkb:Phosphoprotein_p53
gptkb:Tumor_suppressor_p53
gptkb:Transformation-related_protein_53
|
|
gptkbp:associatedWith
|
gptkb:Li-Fraumeni_syndrome
Various cancers
|
|
gptkbp:biologicalProcess
|
DNA repair
Autophagy
Transcription regulation
DNA binding
Apoptosis
Cell cycle arrest
Senescence
|
|
gptkbp:database
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:Entrez_Gene_ID
|
7157
ENSG00000141510
|
|
gptkbp:expressedIn
|
Ubiquitous
|
|
gptkbp:externalLink
|
https://www.uniprot.org/uniprot/P09651
|
|
gptkbp:function
|
gptkb:Transcription_factor
Tumor suppressor
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:hasIsoform
|
Multiple
|
|
gptkbp:HGNC_ID
|
11998
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:locusType
|
17p13.1
|
|
gptkbp:mutationAssociatedWith
|
Frequently mutated in cancer
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
|
gptkbp:orthologIn
|
gptkb:Mouse_Trp53
Rat Tp53
|
|
gptkbp:pathway
|
Cell cycle
p53 signaling pathway
Apoptosis pathway
|
|
gptkbp:PDB
|
gptkb:2OCJ
gptkb:3KMD
gptkb:4HJE
1TUP
5XVK
|
|
gptkbp:postTranslationalModification
|
Phosphorylation
Acetylation
Ubiquitination
|
|
gptkbp:protein_name
|
gptkb:Cellular_tumor_antigen_p53
|
|
gptkbp:refersTo
|
Tumor protein p53
|
|
gptkbp:RefSeq
|
NP_000537.3
|
|
gptkbp:sequence
|
393
|
|
gptkbp:status
|
Reviewed
|
|
gptkbp:subcellularLocation
|
gptkb:Mitochondrion
gptkb:Nucleus
gptkb:Cytoplasm
|
|
gptkbp:bfsParent
|
gptkb:hnRNPA1
gptkb:HNRNPA1
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
P09651
|