|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:HNRPA1
gptkb:heterogeneous_nuclear_ribonucleoprotein_A1
gptkb:hnRNP_A1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:multisystem_proteinopathy
amyotrophic lateral sclerosis
|
|
gptkbp:discoveredBy
|
gptkb:Dreyfuss_laboratory
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:domain
|
RNA recognition motif
glycine-rich domain
|
|
gptkbp:fullName
|
gptkb:Heterogeneous_nuclear_ribonucleoprotein_A1
|
|
gptkbp:function
|
RNA binding
mRNA transport
alternative splicing regulation
|
|
gptkbp:gene
|
gptkb:HNRNPA1
|
|
gptkbp:GO_term
|
GO:0005634
GO:0003723
GO:0008380
|
|
gptkbp:hasIsoform
|
gptkb:hnRNPA1-A
gptkb:hnRNPA1-B
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
hnRNPA1
|
|
gptkbp:interactsWith
|
gptkb:SRSF1
gptkb:hnRNPA2B1
gptkb:importin_beta
|
|
gptkbp:locatedOnChromosome
|
12q13.13
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~38 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Hnrnpa1
|
|
gptkbp:PDB
|
gptkb:1HA1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
|
|
gptkbp:sequence
|
372 amino acids
|
|
gptkbp:subunit
|
homodimer
monomer
|
|
gptkbp:UniProtID
|
gptkb:P09651
|
|
gptkbp:bfsParent
|
gptkb:FUS_protein
|
|
gptkbp:bfsLayer
|
6
|