|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:heterogeneous_nuclear_ribonucleoprotein_A1
gptkb:hnRNP_A1
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:multisystem_proteinopathy
amyotrophic lateral sclerosis
|
|
gptkbp:component
|
nucleoplasm
|
|
gptkbp:discoveredBy
|
Jean D. Dreyfuss
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:domain
|
RNA recognition motif
|
|
gptkbp:encodedBy
|
gptkb:HNRNPA1_gene
|
|
gptkbp:Entrez_Gene_ID
|
3178
ENSG00000135486
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:fullName
|
gptkb:Heterogeneous_nuclear_ribonucleoprotein_A1
|
|
gptkbp:function
|
RNA binding
mRNA transport
alternative splicing regulation
|
|
gptkbp:gene
|
gptkb:HNRNPA1
|
|
gptkbp:GOProcess
|
mRNA processing
|
|
gptkbp:interactsWith
|
gptkb:SMN1
gptkb:SRSF1
gptkb:HNRNPA2B1
gptkb:importin_beta
U2AF2
|
|
gptkbp:locatedOnChromosome
|
12q13.13
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
~34 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:1HA1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
|
|
gptkbp:proteinFamily
|
hnRNP A/B family
|
|
gptkbp:RefSeq
|
NM_002136
|
|
gptkbp:sequence
|
372 amino acids
|
|
gptkbp:subcellularShuttling
|
nucleus-cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P09651
|
|
gptkbp:bfsParent
|
gptkb:HNR
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HNRNPA1
|