|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:IGF-I
Mechano growth factor
Somatomedin A
|
|
gptkbp:chain
|
22-195
|
|
gptkbp:disease_involvement
|
gptkb:cancer
Growth disorders
|
|
gptkbp:Entrez_Gene_ID
|
3479
ENSP00000379323
|
|
gptkbp:function
|
Stimulates growth and has insulin-like metabolic effects
|
|
gptkbp:gene
|
gptkb:IGF1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P08069
|
|
gptkbp:locatedOnChromosome
|
12
12q23.2
|
|
gptkbp:molecularWeight
|
21874 Da
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1IGL
1IMX
1GZR
|
|
gptkbp:postTranslationalModification
|
Disulfide bond
Glycosylation
|
|
gptkbp:protein_name
|
gptkb:Insulin-like_growth_factor_I
|
|
gptkbp:recipient
|
gptkb:INSR
gptkb:IGF1R
|
|
gptkbp:RefSeq
|
gptkb:NP_000609.1
|
|
gptkbp:sequence
|
195
|
|
gptkbp:signalPeptide
|
1-21
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:tissue_specificity
|
Plasma
Liver
Muscle
|
|
gptkbp:UniProtID
|
gptkb:P08069
|
|
gptkbp:bfsParent
|
gptkb:IGF1_receptor
gptkb:IGF-1R
gptkb:insulin-like_growth_factor_1_receptor
|
|
gptkbp:bfsLayer
|
7
|