Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:p53
gptkb:transformation_related_protein_53 |
| gptkbp:biologicalProcess |
transcription factor activity
|
| gptkbp:encodes |
gptkb:tumor_protein_p53
|
| gptkbp:Entrez_Gene_ID |
24842
|
| gptkbp:function |
tumor suppressor
|
| gptkbp:GO_term |
GO:0003677 (DNA binding)
GO:0008285 (negative regulation of cell proliferation) GO:0006977 (DNA damage response) |
| https://www.w3.org/2000/01/rdf-schema#label |
rat Tp53
|
| gptkbp:length |
390 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:mutationAssociatedWith |
loss of function leads to increased tumorigenesis
|
| gptkbp:organism |
gptkb:Rattus_norvegicus
|
| gptkbp:orthologIn |
gptkb:human_TP53
gptkb:mouse_Trp53 |
| gptkbp:pathway |
p53 signaling pathway
|
| gptkbp:product |
gptkb:p53_protein
|
| gptkbp:RefSeq |
NM_030989
|
| gptkbp:regulates |
apoptosis
DNA repair cell cycle senescence |
| gptkbp:UniProtID |
P10361
|
| gptkbp:bfsParent |
gptkb:P04629
|
| gptkbp:bfsLayer |
7
|