|
gptkbp:instanceOf
|
gptkb:receptor_tyrosine_kinase
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:NTRK1
gptkb:tropomyosin_receptor_kinase_A
|
|
gptkbp:binds
|
gptkb:nerve_growth_factor
|
|
gptkbp:biologicalProcess
|
transmembrane receptor protein tyrosine kinase activity
|
|
gptkbp:EC_number
|
2.7.10.1
|
|
gptkbp:encodedBy
|
gptkb:NTRK1_gene
|
|
gptkbp:Entrez_Gene_ID
|
4914
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
sensory neurons
sympathetic neurons
|
|
gptkbp:formsComplexWith
|
gptkb:NGF
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
neurotrophin receptor
|
|
gptkbp:HGNC_ID
|
8031
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TrkA
|
|
gptkbp:involvedIn
|
neuronal differentiation
neuronal survival
pain signaling
|
|
gptkbp:locatedOnChromosome
|
1q23.1
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:congenital_insensitivity_to_pain_with_anhidrosis
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:1WWW
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:target
|
gptkb:entrectinib
gptkb:larotrectinib
|
|
gptkbp:UniProtID
|
gptkb:P04629
|
|
gptkbp:bfsParent
|
gptkb:nerve_growth_factor
|
|
gptkbp:bfsLayer
|
5
|