|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:EC_number
|
3.6.5.2
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000174775
3265
|
|
gptkbp:function
|
gptkb:Signal_transduction
GTPase activity
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
gptkbp:GOID
|
GO:0005525
GO:0007165
GO:0007265
GO:0005886
GO:0003924
GO:0005515
GO:0005737
GO:0007264
GO:0000165
GO:0005829
GO:0005622
|
|
gptkbp:hasDrugBankTargetID
|
BE0000082
|
|
gptkbp:hasGeneCardsID
|
gptkb:HRAS
|
|
gptkbp:hasPfamDomain
|
gptkb:PF00071
|
|
gptkbp:hasRefSeqID
|
gptkb:NP_005334.1
|
|
gptkbp:hasUniGeneID
|
Hs.654682
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01139
|
|
gptkbp:InterPro
|
gptkb:IPR027417
gptkb:IPR001806
IPR003579
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
Cell proliferation
Cell differentiation
|
|
gptkbp:KEGGID
|
gptkb:hsa:3265
|
|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11p15.5
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Colorectal_cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Rhabdomyosarcoma
Lung cancer
|
|
gptkbp:name
|
gptkb:HRAS
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:5P21
gptkb:1QRA
1AA9
3K8Y
1CTQ
4Q21
2Q21
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
gptkb:Cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P01139
|
|
gptkbp:bfsParent
|
gptkb:mouse_NGF
gptkb:rat_NGF
|
|
gptkbp:bfsLayer
|
8
|