Nuclear receptor subfamily 4 group A member 1

URI: https://gptkb.org/entity/Nuclear_receptor_subfamily_4_group_A_member_1
GPTKB entity
Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alsoKnownAs gptkb:TR3
gptkb:NR4A1
gptkb:NGFI-B
gptkb:Nur77
Nerve growth factor IB
gptkbp:associatedWith gptkb:cancer
gptkb:metabolic_syndrome
atherosclerosis
autoimmune diseases
inflammatory diseases
gptkbp:binds gptkb:gene
response elements
gptkbp:discoveredIn 1988
gptkbp:encodedBy NR4A1 gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000105976
3164
gptkbp:expressedIn gptkb:adrenal_gland
gptkb:thymus
brain
liver
many tissues
spleen
gptkbp:function apoptosis
cell proliferation
transcription factor
regulation of gene expression
metabolic regulation
T cell receptor signaling
gptkbp:HGNC_ID 7981
https://www.w3.org/2000/01/rdf-schema#label Nuclear receptor subfamily 4 group A member 1
gptkbp:interactsWith gptkb:Bcl-2
gptkb:CREB-binding_protein
gptkb:RXR_(Retinoid_X_Receptor)
gptkb:p53
gptkb:NCOA1
gptkb:NCOA2
gptkb:NCOA3
gptkbp:locatedOnChromosome chromosome 12q13
gptkbp:memberOf nuclear receptor family
NR4A subfamily
gptkbp:OMIM 139313
gptkbp:orthologInMouse gptkb:Nr4a1
gptkbp:regulates immune response
inflammatory response
cellular differentiation
cellular proliferation
metabolic processes
apoptosis in T cells
gptkbp:UniProtID P22736
gptkbp:bfsParent gptkb:NR4A1
gptkbp:bfsLayer 8