Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Neuroblastoma_RAS_viral_oncogene_homolog
|
| gptkbp:binds |
gptkb:GDP
gptkb:GTP |
| gptkbp:discoveredIn |
1983
|
| gptkbp:encodedBy |
gptkb:NRAS_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
guanine nucleotide exchange factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
NRAS protein
|
| gptkbp:involvedIn |
cell differentiation
cell proliferation cell signaling apoptosis regulation |
| gptkbp:locatedOnChromosome |
chromosome 1
|
| gptkbp:memberOf |
gptkb:RAS_protein_family
|
| gptkbp:molecularWeight |
21 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:acute_myeloid_leukemia colorectal cancer melanoma |
| gptkbp:PDB |
gptkb:3CON
|
| gptkbp:postTranslationalModification |
farnesylation
palmitoylation |
| gptkbp:regulates |
gptkb:MAPK_pathway
gptkb:PI3K-AKT_pathway |
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
gptkb:P01111
|
| gptkbp:bfsParent |
gptkb:NRAS
|
| gptkbp:bfsLayer |
5
|