|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:C/EBP_beta
Nuclear factor interleukin-6
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:diabetes
gptkb:metabolic_syndrome
obesity
inflammatory diseases
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:discoveredBy
|
Akira S et al.
|
|
gptkbp:domain
|
basic leucine zipper (bZIP) domain
|
|
gptkbp:encodedBy
|
gptkb:CEBPB_gene
|
|
gptkbp:Entrez_Gene_ID
|
1051
ENSG00000172216
|
|
gptkbp:expressedIn
|
gptkb:cancer
brain
liver
adipose tissue
macrophages
|
|
gptkbp:firstDescribed
|
1990
|
|
gptkbp:formsHeterodimerWith
|
gptkb:ATF4
C/EBP alpha
C/EBP delta
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:gene
|
CEBPB
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:1834
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NF-IL6
|
|
gptkbp:involvedIn
|
inflammation
immune system regulation
acute phase response
|
|
gptkbp:locatedOnChromosome
|
gptkb:20q13.13
|
|
gptkbp:memberOf
|
gptkb:C/EBP_family
|
|
gptkbp:orthologInMouse
|
gptkb:Cebpb
|
|
gptkbp:phosphorylates
|
gptkb:MAPK
gptkb:GSK3
gptkb:CDK2
|
|
gptkbp:regulates
|
gptkb:TNF-alpha
gptkb:IL-6
apoptosis
cell differentiation
cell proliferation
metabolism
immune response
inflammatory response
acute phase proteins
serum amyloid A
haptoglobin
|
|
gptkbp:UniProtID
|
gptkb:P17676
|
|
gptkbp:bfsParent
|
gptkb:CEBPB_gene
gptkb:C/EBP_beta
|
|
gptkbp:bfsLayer
|
8
|