ERK (extracellular signal-regulated kinase)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:activatedBy	gptkb:MEK1 gptkb:MEK2 phosphorylation
gptkbp:alternativeName	gptkb:ERK1 gptkb:ERK2 MAPK (mitogen-activated protein kinase)
gptkbp:biologicalProcess	serine/threonine kinase activity
gptkbp:discoveredIn	1991
gptkbp:encodedBy	gptkb:MAPK1_gene gptkb:MAPK3_gene
gptkbp:foundIn	eukaryotic cells
gptkbp:function	phosphorylates target proteins
gptkbp:inhibitedBy	gptkb:PD98059 gptkb:U0126
gptkbp:involvedIn	cell differentiation cell proliferation cell survival signal transduction cell cycle regulation
gptkbp:memberOf	gptkb:MAP_kinase_family
gptkbp:regulates	apoptosis gene expression metabolism
gptkbp:subcellularLocation	gptkb:nucleus gptkb:cytoplasm
gptkbp:bfsParent	gptkb:Mitogen-activated_protein_kinases_(MAPKs) gptkb:RTK-RAS-RAF-MEK-ERK_pathway gptkb:Mitogen-activated_protein_kinase_pathway gptkb:Raf/MEK/ERK_cascade
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	ERK (extracellular signal-regulated kinase)