Mitogen-activated protein kinase kinase 4

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:activatedBy	gptkb:JNK gptkb:p38_MAPK
gptkbp:alternativeName	gptkb:MKK4 gptkb:JNKK1
gptkbp:associatedWith	gptkb:cancer pancreatic cancer
gptkbp:biologicalProcess	protein serine/threonine kinase activity
gptkbp:Entrez_Gene_ID	6416
gptkbp:enzymeCommissionNumber	2.7.12.2
gptkbp:expressedIn	many tissues
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	signal transduction phosphorylation kinase activity
gptkbp:gene	gptkb:MAP2K4
gptkbp:HGNC_ID	6840
gptkbp:involves	gptkb:cellular_stress_response apoptosis inflammatory response
gptkbp:length	399
gptkbp:locatedOnChromosome	17p11.2
gptkbp:location	gptkb:nucleus gptkb:cytoplasm
gptkbp:OMIM	602753
gptkbp:part_of_pathway	gptkb:MAPK_signaling_pathway
gptkbp:PDB	3ALO
gptkbp:phosphorylates	gptkb:MAPK9 gptkb:MAPK14 gptkb:MAPK8
gptkbp:RefSeq	NM_003010
gptkbp:regulates	cell differentiation cell proliferation cell survival cell migration
gptkbp:UniProtID	gptkb:P45985
gptkbp:bfsParent	gptkb:MKK4
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Mitogen-activated protein kinase kinase 4