Statements (28)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:protein
                                        
                                         | 
                            
| gptkbp:activatedBy | 
                                    
                                        
                                            gptkb:MAPKKK
                                        
                                         | 
                            
| gptkbp:alternativeName | 
                                    
                                        
                                            gptkb:MEK
                                        
                                         gptkb:MAP2K  | 
                            
| gptkbp:enzymeClassification | 
                                    
                                        
                                            gptkb:EC_2.7.12.2
                                        
                                         | 
                            
| gptkbp:foundIn | 
                                    
                                        
                                            
                                            eukaryotes
                                        
                                        
                                         | 
                            
| gptkbp:fullName | 
                                    
                                        
                                            gptkb:Mitogen-activated_protein_kinase_kinase
                                        
                                         | 
                            
| gptkbp:function | 
                                    
                                        
                                            
                                            phosphorylates MAP kinases (MAPK)
                                        
                                        
                                         | 
                            
| gptkbp:hasIsoform | 
                                    
                                        
                                            gptkb:MEK1
                                        
                                         gptkb:MEK2 gptkb:MKK3 gptkb:MKK4 gptkb:MKK6 gptkb:MKK7 gptkb:MKK5 7  | 
                            
| gptkbp:involvedIn | 
                                    
                                        
                                            gptkb:MAPK_signaling_pathway
                                        
                                         | 
                            
| gptkbp:phosphorylatesResidue | 
                                    
                                        
                                            
                                            serine/threonine
                                        
                                        
                                         | 
                            
| gptkbp:proteinFamily | 
                                    
                                        
                                            gptkb:MAP2K_family
                                        
                                         | 
                            
| gptkbp:regulates | 
                                    
                                        
                                            
                                            apoptosis
                                        
                                        
                                         cell differentiation cell proliferation stress response  | 
                            
| gptkbp:role | 
                                    
                                        
                                            
                                            cellular signal transduction
                                        
                                        
                                         | 
                            
| gptkbp:substrate | 
                                    
                                        
                                            gptkb:MAPK
                                        
                                         | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Ras/MAPK_signaling_pathway
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            6
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            MAPKK
                                        
                                        
                                         |