Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:MAPKKK
|
| gptkbp:alternativeName |
gptkb:MEK
gptkb:MAP2K |
| gptkbp:enzymeClassification |
gptkb:EC_2.7.12.2
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
gptkb:Mitogen-activated_protein_kinase_kinase
|
| gptkbp:function |
phosphorylates MAP kinases (MAPK)
|
| gptkbp:hasIsoform |
gptkb:MEK1
gptkb:MEK2 gptkb:MKK3 gptkb:MKK4 gptkb:MKK6 gptkb:MKK7 gptkb:MKK5 7 |
| https://www.w3.org/2000/01/rdf-schema#label |
MAPKK
|
| gptkbp:involvedIn |
gptkb:MAPK_signaling_pathway
|
| gptkbp:phosphorylatesResidue |
serine/threonine
|
| gptkbp:proteinFamily |
gptkb:MAP2K_family
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation stress response |
| gptkbp:role |
cellular signal transduction
|
| gptkbp:substrate |
gptkb:MAPK
|
| gptkbp:bfsParent |
gptkb:Ras/MAPK_signaling_pathway
|
| gptkbp:bfsLayer |
6
|